FastStrips LLC

Science

Science

Research That Powers Every FastStrip

We are dedicated to advancing the science of nutraceuticals, leveraging research to provide innovative health solutions for all

Trademarked Ingredient Library
  • UC-II® - supports joint mobility and flexibility
  • PureMune™ - supports rapid immune activation
  • ElderMax™- potent antioxidant and anthocyanin content
  • Dermial® - enhances skin hydration, radiance, and collagen renewal
  • Lutemax® 2020 – supports visual and cognitive performance, and blue-light defense
Commitment to Research

We prioritize rigorous research and collaboration with ingredient innovators to develop effective nutraceutical products in advanced ODF formats.

Learn more about our ODF Technology
Clinical Studies/References

Our formulations are built around clinically studied ingredients to support safety and efficacy in real world use.

View studies on our active ingredients
UC-II®️ – HealthFast Joint Strips
  1. Lugo J., et al. 2016 ‘Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study’ Nutrition Journal, Lugo et al. Nutrition Journal (2016) 15:14 DOI 10.1186/s12937-016-0130-8
  2. Rong Xu et al., 2023 ‘ Undenatured type II collagen and its role in improving osteoarthritis’, Ageing Research Reviews 91 (2023) 102080
  3. Pates G. et al., 2023 ‘UC-II®️ undenatured type II collagen data show retention during functional food and beverage prototype processing’, Data in Brief, 109216
  4. Zapata A. and Ferrandez-Parra R., 2023’ Management of Osteoarthritis and Joint Support Using Feed Supplements: A Scoping Revie of Undenatured Type II Collagen and Boswellia serrata’ Animals 2023, 13, 870 https://doi.org/10.3390/ani13050870
  5. Sadigursky D. et al., 2020 ‘ UNDENATURED COLLAGEN TYPE II FOR THE TREATMENT OF OSTEOARTHRITIS OF THE KNEE’ DOI: http://dx.doi.org/10.1590/1413-785220223002240572
  6. Prabhoo R.,  and Billa G., 2018 ‘Undenatured collagen type II for the treatment of osteoarthritis: a review
  7. Crowley D.,et al., 2009, ‘Prabhoo R.,  and Billa G., 2018 ‘Undenatured collagen type II for the treatment of osteoarthritis: a review’ International Journal of Medical Services, 6(6):312-321
  8. Harris R. et al. 2021 ‘Functional Characterization of Undenatured Type II Collagen supplements: Are They Interchangeable?’ doi=10.1080/19390211.2021.1931621
  9. Gencoglu H. et al., 2020 ‘ Undenatured Type II Collagen (UC-II) in Joint Health and Disease: A Review on the Current Knowledge of Companion Animals’ Animals, 4 March 2020; Accepted: 6 April 2020; Published: 17 April 2020
  10. UC-II®️ Undenatured Type II Collagen for Joint Health, Lonza White Paper
Eldermax™️ & PureMune™️ – HealthFast Immune Strips
  1. Ferreira et al . ,’ Elderberry (Sambucus nigra ) extracts promote anti-inflammatory and cellular antioxidant activity’, Food chemistry, 15 (2022) https://doi.org/10.1016/j.fochx.2022.100437
  2. Bagatela B. S., et al. ‘ Effect of Beta-Glucan on the Improvement of Immunity in Healthy Individuals during the Flu Season: A Pilot, Prospective and Open-label Clinical Trial’, HealthMED - Volume 17 / Number 1 / 2023 (Conducted by PureMune™️)
  3. Roschek Jr B., ‘ Elderberry flavonoids bind to and prevent H1N1 infection in vitro’, Phytochemistry 70 (2009) 1255–1261
  4. Silva R. et al., ‘Anthocyanin Profile of Elderberry Juice:
  5. A Natural-Based Bioactive Colouring Ingredient with Potential Food Application’ Molecules 2019, 24, 2359; doi:10.3390/molecules24132359
  6. CINGI C. et al., ‘ Efficacy of traditional herbal formulas on human immunity ’ European Review for Medical and Pharmacological Sciences, 2023; 27 (4 Suppl): 27-40
  7. Cappellucci et al., ‘ Investigation on the Efficacy of Two Food Supplements Containing a Fixed Combination of Selected Probiotics and β-Glucans or Elderberry Extract for the Immune System: Modulation on Cytokines Expression in Human THP-1 and PBMC’ Food 2024, 13, 458 https://doi.org/10.3390/foods13030458
  8. Aguzzi C. et al., ‘ Evaluation of anti-inflammatory and immunoregulatory activities of Stimunex® and Stimunex D3® in human monocytes/macrophages stimulated with LPS or IL-4/IL-13, Biomedicine & Pharmacotherapy 132 (2020) 110845
  9. Sobieralska M. and Kurek Andrzej M., ‘ Beta-Glucan as Wall Material in Encapsulation of Elderberry (Sambucus nigra) Extract’ Plant Foods for Human Nutrition (2019) 74:334-341.
  10. Akramiene et al . ‘ Effects of b-glucans on the immune system’ Medicina (Kaunas) 2007; 43(8)
Hydroxytryptophan (5-HTP) – HealthFast Mood Strips
  1. Massimo E. Maffei, ‘5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology’, International Journal of Molecular Sciences, Int. J. Mol. Sci. 2021, 22, 181. https://dx.doi.org/10.3390/ijms22010181
  2. E.H. Turner, J.M. Loftis, A.D. Blackwell, ‘Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophan’, Pharmacology & Therapeutics, 2006, 109, 325–38.
  3. Károly Mazák* and Béla Noszál, ‘Article Type: Full Paper Passive membrane penetration of the serotonin precursor 5- hydroxytryptophan is controlled by its zwitterion’, Semmelweis University, Department of Pharmaceutical Chemistry
  4. Shell W., et al., ‘A Randomized, Placebo-Controlled Trial of an Amino Acid Preparation on Timing and Quality of Sleep’, American Journal of Therapeutics 17, 133–139 (2010)
  5. Zamoscik et al. ‘Tryptophan‑enriched diet or 5‑hydroxytryptophan Supplementation given in a randomized controlled trial impacts social cognition on a neural and behavioral level’, (2021) 11:21637 | https://doi.org/10.1038/s41598-021-01164-y
  6. Weinberg-Wolf et al., ‘The effects of 5-hydroxytryptophan on attention and central serotonin neurochemistry in the rhesus macaque’ Received: 13 October 2017 Revised: 11 December 2017 Accepted: 17 December 2017 Published online: 30 January 2018.
  7. Shaw K et al., ‘Tryptophan and 5-hydroxytryptophan for depression, Cochrane Database Syst Rev 2001;2002(3):CD003198.DOI: 10.1002/14651858.CD003198
  8. Shaw et al, ‘Are tryptophan and 5-hydroxytryptophan effective treatments for depression? A meta-analysis’, Australian and New Zealand Journal of Psychiatry 2002; 36:488–491
  9. Jauhar S., et al., ‘Fifty years on: Serotonin and depression’, Journal of Psychopharmacology 2023, Vol. 37(3) 237– 241.
Bacillus Clausii – HealthFast Probiotic Strips
  1. Ghelardi E. et al., ‘ Current Progress and Future Perspectives on the Use of Bacillus clausii Microorganism 2022, 10 1246, https://doi.org/10.3390/microorganisms10061246
  2. Abrescia A. et al., ‘Antibiotic Sensitivity of Bacillus clausii Strains in Commercial Preparation’, Clinical Immunology, Endocrine & Metabolic Drugs, 2014, 1, 102-110.
  3. Dang Ha T., et al., ‘ Promising clinical and immunological efficacy of Bacillus clausii spore probiotics for supportive treatment of persistent diarrhea in children’, Scientific reports, (2024) 14:6422 | https://doi.org/10.1038/s41598-024-56627-9.
  4. Plomer M. et al., ‘ Effect of Bacillus clausii Capsules in Reducing Adverse Effects Associated with Helicobacter pylori Eradication Therapy: A Randomized, Double-Blind, Controlled Trial, Infect Dis Ther (2020) 9:867–878 https://doi.org/10.1007/s40121-020-00333-2
  5. Sadrimovahed M. and Ulusoy B., ‘ Bacillus clausii: A Review into Story of Its Probiotic Success and Potential Food Applications’ Fermentation 2024, 10, 522. https://doi.org/10.3390/fermentation10100522
  6. Chelliah R. et al., ‘ Robust and safe: Unveiling Bacillus clausii OHRC1’s potential as a versatile probiotic for enhanced food quality and safety’, Food Science and Technology 203 (2024) 116291 https://doi.org/10.1016/j.lwt.2024.116291
Lutemax 2020 (Lutein and Zeaxanthin) – HealthFast Vision Strips
  1. Stringham et al., ‘ Macular Carotenoid Supplementation Improves Visual Performance, Sleep Quality, and Adverse Physical Symptoms in Those with High Screen Time Exposure’, Foods 2017, 6, 47; doi:10.3390/foods6070047
  2. Parekh et al., ‘Lutein and Zeaxanthin Supplementation Improves Dynamic Visual and Cognitive Performance in Children: A Randomized, Double-Blind, Parallel, Placebo-Controlled Study’, Adv Ther (2024) 41:1496–1511 https://doi.org/10.1007/s12325-024-02785-1
  3. Murillo A. et al., ‘ Zeaxanthin: Metabolism, Properties, and Antioxidant Protection of Eyes, Heart, Liver, and Skin’ Antioxidants 2019, 8, 390; doi:10.3390/antiox8090390
  4. Julie Mares, ‘Lutein and Zeaxanthin Isomers in Eye Health and Disease’ Annu. Rev. Nutr. 2016. 36:571–602, 10.1146/annurev-nutr-071715-051110
  5. Mrowicka et al. ‘ Lutein and Zeaxanthin and Their Roles in Age-Related Macular Degeneration-Neurodegenerative Disease’ Nutrients, 2022 Feb 16;14(4):827. doi: 10.3390/nu14040827.
  6. Hirdyani, H.; Sheth, M. Lutein—The less explored carotenoid. World J. Pharm. Res. 2017, 6, 528–553.
  7. EFSA: Statement on the safety of synthetic zeaxanthin as an ingredient in food supplements. EFSA J. 2012, 10, 2981.
  8. Widomska, J.; SanGiovanni, J.P.; Subczynski, W.K. Why Is Zeaxanthin the Most Concentrated Xanthophyll in the Central Fovea? Nutrients 2020, 12, 1333.
  9. Bernstein, P.S.; Li, B.; Vachali, P.P.; Gorusupudi, A.; Shyam, R.; Henriksen, B.S.; Nolan, J.M. Lutein, zeaxanthin, and mesozeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease. Prog. Retin. Eye Res. 2016, 50, 34–66.
  10. Jarrett, S.G.; Boulton, M.E. Consequences of oxidative stress in age-related macular degeneration. Mol. Asp. Med. 2012, 33, 399–417.
  11. Huang, Y.M.; Dou, H.L.; Huang, F.F.; Xu, X.R.; Zou, Z.Y.; Lin, X.M. Effect of supplemental lutein and zeaxanthin on serum, macular pigmentation, and visual performance in patients with early age-related macular degeneration. Biomed. Res. Int. 2015, 2015, 564738.
  12. Bone, R.A.; Davey, P.G.; Roman, B.O.; Evans, D.W. Efficacy of commercially available nutritional supplements: Analysis of Serum uptake, macular pigment optical density and visual functional response. Nutrients 2020, 12, 1321.
  13. Wolf-Schnurrbusch, U.E.; Zinkernagel, M.S.; Munk, M.R.; Ebneter, A.;Wolf, S. Oral lutein supplementation enhances macular pigment density and contrast sensitivity but not in combination with polyunsaturated fatty acids. Investig. Ophthalmol. Vis. Sci. 2015, 56, 8069–8074.
  14. Akuffo, K.O.; Beatty, S.; Peto, T.; Stack, J.; Stringham, J.; Kelly, D.; Leung, I.; Corcoran, L.; Nolan, J.M. The impact of supplemental antioxidants on visual function in nonadvanced age-related macular degeneration: A head-to-head randomized clinical trial. Investig. Ophthalmol. Vis. Sci. 2017, 58, 5347–5360.
  15. Ma, L.; Yan, S.F.; Huang, Y.M.; Lu, X.R.; Qian, F.; Pang, H.L.; Xu, X.R.; Zou, Z.Y.; Dong, P.C.; Xiao, X.; et al. Effect of lutein and zeaxanthin on macular pigment and visual function in patients with early age-related macular degeneration. Ophthalmology 2012, 119, 2290–2297.
  16. Thurnham, D.I.; Nolan, J.M.; Howard, A.N.; Beatty, S. Macular response to supplementation with differing xanthophyll formulations in subjects with and without age-related macular degeneration. Graefe’s Arch. Clin. Exp. Ophthalmol. 2015, 253, 1231–1243.
  17. Murray, I.J.; Makridaki, M.; van der Veen, R.L.; Carden, D.; Parry, N.R.; Berendschot, T.T. Lutein supplementation over a one-year period in early AMD might have a mild beneficial effect on visual acuity: The CLEAR study. Investig. Ophthalmol. Vis. Sci. 2013, 54, 1781–1788.
  18. Johnsons E., ‘A possible role for lutein and zeaxanthin in cognitive function in the elderly’, A m J Clin Nutr 2012;96(suppl):1161S–5S. Printed in USA. 2012 American Society for Nutrition.
  19. Lindbergh et al., ‘Lutein and Zeaxanthin Influence Brain Function in Older Adults: A Randomized Controlled Trial’ J Int Neuropsychol Soc.  2018 Jan;24(1):77-90. doi: 10.1017/S1355617717000534. Epub 2017 Jul 11.
D3K2 – Vitamin D3K2 Strips
  1. Hasific et al., ‘Effects of vitamins K2 and D3 supplementation in patients with severe coronary artery calcification: a study protocol for a randomised controlled trial’ Hasific S, et al. BMJ Open 2023;13:e073233. doi:10.1136/bmjopen-2023-073233
  2. Sattar M. and Lane E.M., ‘ Oral transmucosal drug delivery – _Current status and future prospects’ International Journal of Pharmaceutics’ 2014 http://dx.doi.org/10.1016/j.ijpharm.2014.05.043,
  3. Zhu Y. et al.’ Effect of taste masking technology on fast dissolving oral film: dissolution rate and bioavailability’ Nanotechnology 29 (2018) 304001, https://doi.org/10.1088/1361-6528/aac010maiti
  4. Koziol-Kozakowska A., AND Maresz K. ‘ The Impact of Vitamin K2 (Menaquionones) in Children’s Health and Diseases: A Review of the Literature’ Children 2022, 9, 78. https://doi.org/10.3390/children9010078
  5. Pritchard L. et al., ‘ Comparative effectiveness of vitamin D supplementation via buccal spray versus oral supplements on serum 25-hydroxyvitamin D concentrations in humans: a systematic review protocol’ JBI Database of Systematic Reviews and Implementation Reports DOI: 10.11124/JBISRIR-2017-003907
  6. Luo G, Ducy P, McKee MD, et al. Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. Nature 1997;386:78–81.
  7. Ballegooijen A. et., ‘ The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review’ International Journal of Endocrinology https://doi.org/10.1155/2017/7454376
  8. Xie Y. et al. ‘ Vitamin K: Infection, Inflammation, and Auto-Immunity’, Journal of Inflammation Research 2024; 17 1147-1160.
  9. Schwalfenberg G. K., ‘ Vitamins K1 and K2: The Emerging Group of Vitamins Required for Human Health’ Hindawi Journal of Nutrition and Metabolism Volume 2017, Article ID 6254836, 6 pages https://doi.org/10.1155/2017/6254836
  10. Benedik E., ‘Sources of vitamin D for humans’ Int J Vitam Nutr Res (2022), 92 (2), 118–125
  11. Pela I., ‘How much vitamin D for children?’, Clinical Cases in Mineral and Bone Metabolism 2012; 9(2): 112-117
  12. Spiro A. and Buttriss J.L. ‘ Vitamin D:An overview of vitamin D status and intake in Europe’ Nutrition Bulletin
  13. Carbonare L. D. Et al.’ Vitamin D: Daily vs. Monthly Use in Children and Elderly—What Is Going On?’ Nutrients 2017, 9, 652; doi:10.3390/nu9070652
  14. Vitamin K Fact Sheet for Halth Professionals, National Institues of Health Office of Dietary Supplements
  15. Kuang X . et al .’ The combination effect of vitamin K and vitamin D on human bone quality: a meta-analysis of randomized controlled trials’ Food&Function, Food Funct., 2020, DOI: 10.1039/C9FO03063H.
  16. Todd J. et al .’ Vitamin D3 supplementation in healthy adults: a comparison between capsule and oral spray solution as a method of delivery in a wintertime, randomised, open-label, cross-over study’ British Journal of Nutrition (2016), 116, 1402–1408.
  17. Mandeep K. et al. ‘ Fast Dissolving Films: An Innovative Drug Delivery System’ International Journal of Pharmaceutical Research & Allied Sciences, Volume 2, issue 1 (2013), 14-24.
  18. Ketul P. et al. ‘ Fast Dissolving Films: A Novel Approach to Oral Drug Delivery’, International Journal of Pharmacy Teaching & Practices 2013, Vol.4, Issue 2, 655-661.
  19. Dinesh Wanjari. ‘ An overview on fast dissolving oral strip http://dx.doi.org/10.21746/ijbio.2014.07.0015
  20. Zhang H. et al.’ Oral Mucosal Drug Delivery Clinical Pharmacokinetics and Therapeutic Applications’ Clin Pharmacokinetics an 2002; 41 (9): 661-680 0312-5963/02/0009-0661/$25.00/0
  21. Bala R. et al. ‘ Orally dissolving strips: A new approach to oral drug delivery system’ International Journal of Pharmaceutical Investigation | April 2013 | Vol 3 | Issue 2
UC-II®️ – PetFast Mobility Strips
  1. D’Altilio et al, Toxicology Mechanisms and Methods, 2007 (Based on a 120-day clinical study comparing 10 mg active Type II Collagen to 2 g glucosamine and 1,6 g chondroitin)
  2. Lugo et al., ‘Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study,. Nutrition Journal (2016) 15:14, DOI 10.1186/s12937-016-0130-8
  3. Gencoglu et al., 2020, ‘ Undenatured Type II Collagen (UC-II) in Joint Health and Disease: A Review on the Current Knowledge of  Companion Animals’ Animals 2020, 10, 697; doi:10.3390/ani10040697
  4. Cupta et al, 2012 ‘ Comparative therapeutic efficacy and safety of type-II collagen (UC-II), glucosamine and chondroitin in arthritic dogs: pain evaluation by ground force plate, https://pubmed.ncbi.nlm.nih.gov/21623931/
  5. Evaluation of the Effects of Undenatured Type II Collagen (UC-II) as Compared to Robenacoxib on the Mobility Impairment Induced by Osteoarthritis in Dogshttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789547/
  6. Lee et al., ‘Anti-aging effect of an oral disintegrating collagen film: a prospective, single-arm study’, International Journal of Dermatology, doi: 10.1111/ijd.15675
  7. Sattar et al., ‘Oral transmucosal drug delivery – Current status and future prospects’ International Journal of Pharmaceutics, 2014, Volume 471, Issues 1–2, 25 August 2014, Pages 498-506
  8. Ying Zhu et al., ‘Effect of taste masking technology on fast dissolving oral film: dissolution rate and bioavailability 2018 Nanotechnology 29 304001
  9. Sadigursky ET AL., 2022, ‘Undenatured collagen type II for the treatment of osteoarthritis: a review, https://doi.org/10.1590/1413-785220223002240572